Tyrosine Supplementation A Nutraceutical Approach to Counter Heat Stress Induced Cognitive Decline

Supplementation of tyrosine, non-essential amino acid, and precursor catecholamine was found to ameliorate the heat-induced alterations in latencies event-related potential P300 contingent negative variation. Here we present effect tyrosine supplementation on heat stress (exposure ambient temperature 45 oC relative humidity 30 %) induced behavior (attention, mood) levels plasma monoamines. Ten healthy male participants received a placebo food bar or tyrosine-containing (6.5 g 50 g) 90 min before exposure min. Plasma urine samples were assayed for levels, their precursor, metabolites using high-performance liquid chromatography. A computer-based automated test battery used assess attention mood by profile states questionnaire. significantly higher (p<0.001) leading an increased norepinephrine (p<0.05) supplemented group observed. Selective sustained (p<0.02) better compared group. Reaction time anger scores decreased with supplementation. It may be concluded that improves stress-induced decrement maintaining synthesis turnover norepinephrine.